diff --git a/egui/src/grid.rs b/egui/src/grid.rs
index 13d5e7ba..3b4c224d 100644
--- a/egui/src/grid.rs
+++ b/egui/src/grid.rs
@@ -100,6 +100,15 @@ impl GridLayout {
         Rect::from_min_size(cursor, size)
     }
 
+    pub(crate) fn align_size_within_rect(&self, size: Vec2, frame: Rect) -> Rect {
+        // TODO: allow this alignment to be customized
+        Align2::LEFT_CENTER.align_size_within_rect(size, frame)
+    }
+
+    pub(crate) fn justify_or_align(&self, frame: Rect, size: Vec2) -> Rect {
+        self.align_size_within_rect(size, frame)
+    }
+
     pub(crate) fn advance(&mut self, cursor: &mut Pos2, frame_rect: Rect, widget_rect: Rect) {
         self.curr_state
             .set_min_col_width(self.col, widget_rect.width());
@@ -145,6 +154,10 @@ impl GridLayout {
 
 /// A simple `Grid` layout.
 ///
+/// The contents of each cell be aligned to the left and center.
+/// If you want to add multiple widgets to a cell you need to group them with
+/// [`Ui::horizontal`], [`Ui::vertical`] etc.
+///
 /// ```
 /// # let ui = &mut egui::Ui::__test();
 /// egui::Grid::new("some_unique_id").show(ui, |ui| {
@@ -196,7 +209,11 @@ impl Grid {
             min_row_height,
         } = self;
 
-        ui.wrap(|ui| {
+        // Each grid cell is aligned LEFT_CENTER.
+        // If somebody wants to wrap more things inside a cell,
+        // then we should pick a default layout that matches that alignment,
+        // which we do here:
+        ui.horizontal(|ui| {
             let id = ui.make_persistent_id(id_source);
             let grid = GridLayout {
                 striped,
diff --git a/egui/src/layout.rs b/egui/src/layout.rs
index 4a024a4b..9c2e3f45 100644
--- a/egui/src/layout.rs
+++ b/egui/src/layout.rs
@@ -432,16 +432,27 @@ impl Layout {
 
     /// Apply justify or alignment after calling `next_space`.
     pub(crate) fn justify_or_align(&self, rect: Rect, mut child_size: Vec2) -> Rect {
-        if self.main_dir.is_horizontal() {
-            if self.cross_justify {
+        if self.cross_justify {
+            if self.main_dir.is_horizontal() {
                 child_size.y = rect.height(); // fill full height
-            }
-            Align2([Align::Center, self.cross_align]).align_size_within_rect(child_size, rect)
-        } else {
-            if self.cross_justify {
+            } else {
                 child_size.x = rect.width(); //  fill full width
             }
-            Align2([self.cross_align, Align::Center]).align_size_within_rect(child_size, rect)
+        }
+
+        match self.main_dir {
+            Direction::LeftToRight => {
+                Align2([Align::Min, self.cross_align]).align_size_within_rect(child_size, rect)
+            }
+            Direction::RightToLeft => {
+                Align2([Align::Max, self.cross_align]).align_size_within_rect(child_size, rect)
+            }
+            Direction::TopDown => {
+                Align2([self.cross_align, Align::Min]).align_size_within_rect(child_size, rect)
+            }
+            Direction::BottomUp => {
+                Align2([self.cross_align, Align::Max]).align_size_within_rect(child_size, rect)
+            }
         }
     }
 
diff --git a/egui/src/placer.rs b/egui/src/placer.rs
index e7edca6b..54194feb 100644
--- a/egui/src/placer.rs
+++ b/egui/src/placer.rs
@@ -58,7 +58,11 @@ impl Placer {
 
 impl Placer {
     pub(crate) fn align_size_within_rect(&self, size: Vec2, outer: Rect) -> Rect {
-        self.layout.align_size_within_rect(size, outer)
+        if let Some(grid) = &self.grid {
+            grid.align_size_within_rect(size, outer)
+        } else {
+            self.layout.align_size_within_rect(size, outer)
+        }
     }
 
     pub(crate) fn available_rect_before_wrap(&self) -> Rect {
@@ -102,7 +106,11 @@ impl Placer {
 
     /// Apply justify or alignment after calling `next_space`.
     pub(crate) fn justify_or_align(&self, rect: Rect, child_size: Vec2) -> Rect {
-        self.layout.justify_or_align(rect, child_size)
+        if let Some(grid) = &self.grid {
+            grid.justify_or_align(rect, child_size)
+        } else {
+            self.layout.justify_or_align(rect, child_size)
+        }
     }
 
     /// Advance the cursor by this many points.
@@ -115,7 +123,7 @@ impl Placer {
     }
 
     /// Advance cursor after a widget was added to a specific rectangle
-    /// and expand the region min_rect.
+    /// and expand the region `min_rect`.
     ///
     /// * `frame_rect`: the frame inside which a widget was e.g. centered
     /// * `widget_rect`: the actual rect used by the widget
diff --git a/egui/src/widgets/separator.rs b/egui/src/widgets/separator.rs
index 53507c9a..9e3605be 100644
--- a/egui/src/widgets/separator.rs
+++ b/egui/src/widgets/separator.rs
@@ -4,11 +4,15 @@ use crate::*;
 #[must_use = "You should put this widget in an ui with `ui.add(widget);`"]
 pub struct Separator {
     spacing: f32,
+    is_horizontal_line: Option<bool>,
 }
 
 impl Separator {
     pub fn new() -> Self {
-        Self { spacing: 6.0 }
+        Self {
+            spacing: 6.0,
+            is_horizontal_line: None,
+        }
     }
 
     /// How much space we take up. The line is painted in the middle of this.
@@ -16,31 +20,53 @@ impl Separator {
         self.spacing = spacing;
         self
     }
+
+    /// Explicitly ask for a horizontal line.
+    /// By default you will get a horizontal line in vertical layouts,
+    /// and a vertical line in horizontal layouts.
+    pub fn horizontal(mut self) -> Self {
+        self.is_horizontal_line = Some(true);
+        self
+    }
+
+    /// Explicitly ask for a vertical line.
+    /// By default you will get a horizontal line in vertical layouts,
+    /// and a vertical line in horizontal layouts.
+    pub fn vertical(mut self) -> Self {
+        self.is_horizontal_line = Some(false);
+        self
+    }
 }
 
 impl Widget for Separator {
     fn ui(self, ui: &mut Ui) -> Response {
-        let Separator { spacing } = self;
+        let Separator {
+            spacing,
+            is_horizontal_line,
+        } = self;
+
+        let is_horizontal_line =
+            is_horizontal_line.unwrap_or_else(|| !ui.layout().main_dir().is_horizontal());
 
         let available_space = ui.available_size_before_wrap_finite();
 
-        let size = if ui.layout().main_dir().is_horizontal() {
-            vec2(spacing, available_space.y)
-        } else {
+        let size = if is_horizontal_line {
             vec2(available_space.x, spacing)
+        } else {
+            vec2(spacing, available_space.y)
         };
 
         let (rect, response) = ui.allocate_at_least(size, Sense::hover());
-        let points = if ui.layout().main_dir().is_horizontal() {
-            [
-                pos2(rect.center().x, rect.top()),
-                pos2(rect.center().x, rect.bottom()),
-            ]
-        } else {
+        let points = if is_horizontal_line {
             [
                 pos2(rect.left(), rect.center().y),
                 pos2(rect.right(), rect.center().y),
             ]
+        } else {
+            [
+                pos2(rect.center().x, rect.top()),
+                pos2(rect.center().x, rect.bottom()),
+            ]
         };
         let stroke = ui.style().visuals.widgets.noninteractive.bg_stroke;
         ui.painter().line_segment(points, stroke);
diff --git a/egui_demo_lib/src/apps/demo/widget_gallery.rs b/egui_demo_lib/src/apps/demo/widget_gallery.rs
index f4b2e230..b3ab79ac 100644
--- a/egui_demo_lib/src/apps/demo/widget_gallery.rs
+++ b/egui_demo_lib/src/apps/demo/widget_gallery.rs
@@ -131,7 +131,9 @@ impl super::View for WidgetGallery {
             ui.end_row();
 
             ui.label("Separator:");
-            ui.separator();
+            // Putting a separator in a grid is kind of meaningless since there is no well-defined direction.
+            // Normally you'd just do ui.separator(), but here we need to explicitly pick a dimension:
+            ui.add(egui::Separator::new().horizontal());
             ui.end_row();
 
             ui.label("CollapsingHeader:");